According to the current analysis of Reports and Data, The global Immunohistochemistry market was valued at USD 1,736.4 million in 2018 and is expected to reach USD 3,359.8 million by the year 2026, growing at a CAGR of 8.6%.
Immunohistochemistry (IHC) has crucial applications in the field of tissue distribution of antigens by using monoclonal and polyclonal antibodies. It is used for cancer diagnosis, because it determines the presence of tumor antigens. It is a technique which combines immunological, anatomical, and biochemical processes to identify tissue components by the interaction of target antigens with specific antibodies that are tagged by a label. Immunohistochemistry used by public and private organizations to check localization and distribution of cellular components within the cells.
Immunohistochemistry is being applied in many other areas. Immunohistochemistry is widely used to predict therapeutic response in two important tumors, i.e. carcinoma of breast and prostate. Both these tumors are under the growth regulation of the hormones estrogen and androgen, respectively. The specific receptors for these growth regulating hormones are located on respective tumor cells. Tumors expressing high level of receptor positivity would respond favorably to removal of the endogenous source of such hormones or hormonal therapy is administered to lower their levels – estrogen therapy in prostate cancer and androgen therapy in breast cancer. Immunohistochemistry techniques are also being applied to confirm infectious agent in tissues by use of specific antibodies against microbial DNA or RNA, e.g. in Cytomegalo virus, Hepatitis B virus, Hepatitis C virus, etc. The application is used routinely in validation of disease targets as it allows visualizing expression of the target in the affected tissue during the disease process. Another important advantage of Immunohistochemistry is that it can also be used to detect organisms in cytological preparations such as fluids, sputum samples, and material obtained from fine needle aspiration procedures. This can be very helpful in certain situations such as detection of pneumocystis from the sputum of an immunocompromised patient who needs rapid and precise confirmation of infection in order to begin immediate and appropriate therapy.
Specific diagnosis of muscular dystrophy is important because of the genetic counseling implications of inherited disease and accurate prognostication. In recent years, abnormalities in several muscle proteins have been identified in muscular dystrophies. Such abnormalities involve proteins located in the sarcolemma, extracellular matrix, cytosol, nucleus, and other sites within muscle fibers. Skeletal muscle biopsy can play a main role in differentiating vascular dystrophy from non-dystrophic disorders and Immunohistochemistry can assist in establishing a specific diagnosis of the dystrophies for which specific protein abnormalities are known. In the last few years, immunohistochemical staining for beta amyloid precursor protein has been validated as a method to detect axonal injury within as little as 2–3 h of head injury. Immunohistochemical detection of axonal injury can be useful in establishing timing of a traumatic insult in medico-legal settings.
Rapid growth of healthcare investment in emerging economies and technological development in invitro industry creates the opportunities to manufacturers for Immunohistochemistry kit, equipment and reagents. Growing prevalence of chronic diseases including cancer, cardiovascular diseases, infectious diseases, autoimmune diseases, diabetes mellitus, and nephrological diseases are the key factors for the growth of the market. Significant rise in R&D spending and shift towards comprehensive healthcare solutions are impelling the market growth.
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The report provides an in-depth analysis of the key developments and innovations of the market such as research and development advancements, product launches, mergers & acquisitions, joint ventures, partnerships, government deals, and collaborations. The report offers a comprehensive assessment of key players in the market along with their global position, financial standing, business expansion plans, production and manufacturing capacity, and strategic alliances.
Key players in the market include
Abcam plc; Agilent Technologies; Bio-Rad Laboratories, Inc.; Cell Signaling Technology, Inc.; Danaher Corporation; Merck KGaA; PerkinElmer, Inc.; and Thermo Fisher Scientific, Inc.
For a better understanding of the global Immunohistochemistry market dynamics, a regional analysis of the market across key geographical areas is offered in the report. The market is spread across key geographical regions such as North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. Each region is analysed on the basis of the market scenario in the major countries of the regions to provide a deeper understanding of the market. It provides insights into production and consumption patterns, supply and demand ratio, export/import, current and emerging trends and demands, market share, market size, revenue contribution, and presence of key players in each region.
Furthermore, the report segments Immunohistochemistry market on the basis of key product types and applications and provides details about the revenue growth, revenue CAGR, and revenue share each segment is expected to register over the forecast period.
Type (Revenue, USD Million; 2017–2027)
Application (Revenue, USD Million; 2017–2027)
End Use (Revenue, USD Million; 2017–2027)
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In-depth regional analysis includes:
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