3D Cell Culture is defined as a practice of growing biological cells and allow them to interact with their surroundings in all three dimensions. This technique enables the cells to grow in their natural environment in an in vivo condition. Numerous techniques are used to carry out culturing of cells in all the three dimensions. 3-dimension cell culture is a man-made environment. Cells grown in 3-dimension cell culture with similar properties of cells found inside living organisms in terms of cellular characteristics & behavior.
As three-dimension cell cultures can mimic the structure, activity, as well as microenvironment of the in-vivo tissues, this technique has varied applications in the fields of regenerative medicine, drug screening, stem cell therapies, cancer research & cell biology. The extracellular matrix in three-dimension cell cultures alows cell–cell communication by direct contact as in in-vivo environment by secreting cytokines & trophic factors. These factors are changed in a 2D environment which can significantly affect the cell–cell communication, which in turn can alter the cell morphology & proliferation. As 2-Dimesion cultures cannot recapitulate the architecture & complex cellular matrices as in 3-Dimension cultures, this technique is gaining popularity in healthcare research industry. Also, 3D cell cultures can offer results with improved efficiency & reduce the cost of overall research and development process.
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Lack of consistency in products is anticipated hamper growth of the global 3D cell culture market. The lack of consistency between wells & batches of cell culture are the other major challenges in the adoption of 3D cell culture. In addition, matrices made from animal tissues may contain unwanted growth factors & viruses, which could negatively affect the cell culture productivity &reproducibility.
Impact of COVID-19
The COVID-19 crisis has resulted in nationwide lockdowns, thereby impacting every industry, Likewise, market is also affected by the pandemic. The 3D cell culture industry is facing various challenges to cope up with the demand & supply of 3D cell culture components due to the COVID-19 crisis. Furthermore, inconsistent &interrupted supply chain activities and availability of human resources are projected to impact the market growth. Moreover, surge in research practices for developing novel therapies against COVID-19 (Coronavirus) is serving as a huge opportunity for the key market players. Research associated with stem cell therapies and regenerative medicine has shown promising results for treating the COVID-19, this is anticipated to compensate the deleterious impact caused by lockdowns across the globe. Thus, the overall COVID-19 impact is expected to remain moderate for the prominent players in the global 3D cell culture market.
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Market Key Players
Various key players are listed in this report such as Thermo Fisher Scientific, Inc., Merck KGaA, PromoCell GmbH, Corning, Inc., Greiner Bio One International GmbH, 3D Biomatrix, Lonza, Tecan Trading AG, 3D Biotek LLC, Global Cell Solutions, Inc., InSphero, etc.
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