Market Research Future (MRFR) believes that the cell line development market could surpass USD 10,700 million by the end of the review period. MRFR also expects the global industry to expand at a rate of around 12.5% from 2020 to 2027.
Primary Boosters and Challenges
Several biopharma vendors make extensive use of cells, which work as expression hosts to produce recombinant monoclonal antibodies. The mounting need for monoclonal antibodies and effective cancer therapeutics, along with the emergence and use of cutting-edge techniques for novel cell line production has resulted in considerable revenue generation in recent years. Moreover, surging focus on developing biosimilars due to patent expiry of established therapeutics and recombinant proteins will further push the market demand.
Disconcerting rise in chronic diseases across the world has fostered the need for efficient and innovative treatment solutions, leading to significant requirement for biosimilars, vaccines, proteins, and novel drugs. This is touted to create favorable avenues for the global market, in terms of revenues over the ensuing years. Several risks associated with cell line development, such as random alternations, contamination, and misidentification, can act as growth impediments for the global market in subsequent years.
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On the bright side, the mounting utilization of regenerative medicine, surge in healthcare expenditure, and substantial investments in the biotechnology industry should also benefit the global market in the next few years. Within the biotechnology sector, drug discovery, gene therapy, and cell culture are some of the major applications of cell line development and will be responsible for strong product demand in the following years.
COVID-19 has had a disastrous impact on the healthcare sector, as numerous production facilities forced to shut down and product demand plummeting rapidly. With healthcare’s focus mostly on finding SARS-CoV-2 vaccine, other areas had to take a backseat.
Having said that, it is expected that with operations across the globe resuming and the lockdowns being lifted up, the global cell line development industry can again gain significant traction in the coming period. Also, since the biopharmaceutical sector is emerging as a major end-user, and is increasingly using cell line development techniques, it is presumed that the global market will note sustained growth throughout the evaluation period.
Type, product, source, and application have been covered in the report as major segments, to present a detailed outline of the cell line development industry.
Different types of cell lines are Primary cell, Hybridoma Cell Line, Continuous Cell Line, and Recombinant Cell Line. Primary cell line is on track to be the fastest-progressing segment over the years ahead, considering its rising applications in cell metabolism, cell morphology, and genetics.
Products considered are Media and Reagents as well as Equipment. Media and reagents category has taken the leading place in the market, in view of the surging adoption of these products for cell line development.
Source-based market segments include Mammalian cells, non-Mammalian cells and others. Mammalian cells could be the leading segment between 2020 and 2027, in view of their rising usage in the production of monoclonal antibodies (mAbs).
Major applications covered in the MRFR study are Tissue Engineering, Drug Discovery, Bioproduction, and more. The leading spot belongs to the bioproduction segment, on account of cell lines’ rising use in bioproduction, accelerated number of antibiotics, along with vaccine production.
The biggest gainer out of all the regions is North America, wherein the cell line development market is thriving backed by the mounting need for effective therapeutics to detect cancer as well as auto immune disorders. Escalating use of modern techniques for bioproduction also add to the market worth in the region. Widely known vendors based in the region are focused on product innovations and also enter into partnerships and collaborations to up their business prospects. Some of these companies are Sigma-Aldrich Corporation (US), Thermo Fisher Scientific Inc. (US), and American Type Culture Collection (ATCC), to name a few.l
The key market participants listed in the MRFR report are Selexis SA (Switzerland), Lonza Group AG (Switzerland), American Type Culture Collection (ATCC) (US.), Thermo Fisher Scientific, Inc. (US.), Sigma-Aldrich Corporation (U.S.), GE Healthcare (US.), Corning, Inc. (US.), Promega Corporation (US), WuXiAppTec, Inc. (China), Sartorious AG (Germany), and many more.
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These players strive to widen their global presence while focusing on coming up with highly advanced products via numerous strategies like collaborations, and partnerships. To cite an instance, in July 2021, Catalent introduced its next-generation latest cell line development technology called GPEx Lightning. Backed by the company’s GPEx expression platform within a glutamine synthase knock-out Chinese hamster ovary cell line system, the technology combines cutting-edge technologies, such as novel gene insertion technology that helps reduce the total drug substance development by roughly three months, which is much shorter than previous timelines.
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