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The single-use Bioreactor Market size is estimated to reach $9.67 billion by 2027, growing at a CAGR of 19.8% during the forecast period 2022-2027. A single-use bioreactor or disposable bioreactor is a bioreactor with a disposable bag rather than a culture vessel. Conventionally, this indicates a bioreactor in which the lining associated with the cell culture will be plastic, and this lining is sheathed inside a more lasting structure (usually, either a rocker or a cuboid or cylindrical steel support). Single-use media bags and containers offer a single-use disposable substitute to conventional glass and fixed plastic carboys in a big assortment of bioprocess uses. Single-use filtration assemblies are utilized as a substitute to the conventional stainless-steel systems owing to their ability to destroy the possibilities of infection by related authorization protocols and administering sterilization steps. Single-use bioreactors are extensively utilized in the mammalian cell culture sector and are presently very quickly displacing typical bioreactors. Investigations on the single-use bioreactors for the clinical generation of monoclonal antibodies have been carried out.
The accelerated acceptance of single-use technologies (SUTs) in fields like mammalian cell culture by the industry is set to drive the Single-use Bioreactor Market. The increased cost-effectiveness, reduced downtime, and introduction of novel products is set to propel the growth of the Single-use Bioreactor Market during the forecast period 2022-2027. This represents the Single-use Bioreactor Industry Outlook.
Single-use Bioreactor Market Segment Analysis – By Product Type
The Single-use Bioreactor Market based on product type can be further segmented into Single-use Bioreactor Systems, Media Bags, Filtration Assemblies, and Others. The Single-use Bioreactor Systems Segment held the largest market share in 2021. This growth is owing to proliferating acceptance of single-use bioreactor systems in contemporary biopharmaceutical procedures which may be applied in mammalian cell culture. The improved adaptability minimized financing, and restricted operational costs in conjunction with industrial benefits making single-use bioreactors appealing for multiproduct facilities with up to 6,000 liters are further propelling the growth of this segment.
Furthermore, the Media Bags segment is estimated to grow with the fastest CAGR of 20.6% during the forecast period 2022-2027 owing to the extensive adaptability, lesser lead-times reducing the capital spend, minimized cross-contamination hazard, and the ability for decreased volumes per batch in conjunction with increased use of single-use bioreactors in mammalian cell culture.
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Single-use Bioreactor Market Segment Analysis – By Cell Type
The Single-use Bioreactor Market based on cell type can be further segmented into Mammalian cells, Bacteria, Yeast, and Others. The Mammalian Cell Segment held the largest market share in 2021. This growth is owing to the increased acceptance of mammalian cells owing to their greatly mechanized metabolic equipment. Presently, Sartorius has developed an assortment of single-use bioreactors perfect for mammalian cell culture. The increasing innovations targeted towards the surging usage of single-use bioreactors in mammalian cell culture are further propelling the growth of this segment.
Furthermore, the Bacteria segment is estimated to grow with the fastest CAGR of 20.8% during the forecast period 2022-2027 owing to the proliferating development of Single-Use Bioreactors specially designed for a strong microbial application utilizing bacteria in conjunction with the expanding application of single-use bioreactors in mammalian cell culture.
Single-use Bioreactor Market Segment Analysis – By Geography
The Single-use Bioreactor Market based on geography can be further segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. North America (Single-use Bioreactor Market) held the largest share with 34% of the overall market in 2021. The growth of this region is owing to the increasing count of partnerships between industries and academic institutions and the surging application of single-use bioreactors in mammalian cell culture in the region. These kinds of collaborations influencing the R&D assets of different universities in conjunction with the commercial therapeutics and vaccine development are propelling the growth of the Single-Use Bioreactor Market in the North American region.
Furthermore, the Asia-Pacific region is estimated to be the region with the fastest CAGR rate over the forecast period 2022-2027. This growth is owing to factors like considerable financing by key players and burgeoning government backing. The developing R&D infrastructure in conjunction with the accelerated application of single-use bioreactors in mammalian cell culture is fuelling the progress of the Single-use Bioreactor Market in the Asia-Pacific region.
Single-use Bioreactor Market Drivers
Increased Application Of Single-Use Bioreactor In Mammalian Cell Culture Is Projected To Drive The Growth Of Single-Use Bioreactor Market:
Rather than culture vessels made from stainless steel or glass, a single-use bioreactor is outfitted with a disposable vessel, that comes pre-assembled with all accessories and gamma-irradiated, leaving it aseptic and accessible. Bionet´s SU vessel has commensurate functionality to traditional glass bioreactors. It integrates the uniformity and control capacity of a stirred tank design with the adaptability of single-use, permitting association with any F0 Plug&Play added modules. The SU vessel has been planned for cell culture uses like mammalian cell culture. The DO is offered uninterruptedly by way of aeration instruments, which include the supply of oxygen by way of both the open pipe sparger, micro-sparger, and overlay. CO2 can be selected as an acid agent for pH control. The increased usage of single-use bioreactors in mammalian cell culture is therefore fuelling the growth of the Single-use Bioreactor Market during the forecast period 2022-2027.
Technological Innovations Are Expected To Boost The Demand Of Single-Use Bioreactors:
Technological innovations are driving the growth of the Single-use Bioreactor market. Single-Use Bioreactors find great application in mammalian cell culture. Currently, Sartorius has developed single-use bioreactors that have entrenched themselves in contemporary biopharmaceutical procedures. This is directly connected to their rare capability to improve adaptability, minimize investment and restrain operational costs. Presently, Sartorius provides an extensive assortment of single-use bioreactors which are perfect for mammalian cell culture, very challenging high cell-density or microcarrier-based procedures. The single-use bioreactors from 15 mL working volume with Ambr® 15 to Biostat® STR 2,000 L have been established to guarantee effortless and direct scale-up and scale-down. Integrated with exceptional great performance even at a big scale this makes the products ideally suited to service all the present and forthcoming requirements from process development to commercial production stages. One of the essential constituents of the single-use bioreactors is the Flexsafe® film. Flexsafe® guarantees superior and re-creatable growth behavior of the most sensitive cell lines and satisfies the need for excellent strength and effortless utilization all through the steps. It will offer an exceptional affirmation of supply. The long-term strategic partnership with resin and film suppliers guarantees complete traceability. These kinds of technological advancements are driving the growth of the Single-Use Bioreactor Market during the forecast period 2022-2027.
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Single-use Bioreactor Market Challenges
Impediments To Acceptance Of Single-Use Bioreactors Are Challenging The Growth Of The Single-Use Bioreactors Market:
The present trend in biopharmaceutical production is to develop a tailor-made plant for the given molecule as per its particular bioprocessing need. However, molecules do not function in the same manner at the time of the development, scale-up, or manufacturing stages. Customizing single-use bioreactors to make them suited for processing particular molecules beats their principal benefit of plug and play. The success of developmental trials to make perfect the procedure conditions for production relies on the application of those parameters in the scale-up and production scale procedures. The accessibility of single-use bioreactors that can convert those accurate conditions at large fermentation volumes is a principal challenge. Volume size is limited (no more than 2000 L) and questions still linger pertaining to the quality of the end-product subsequent to large-scale production. These issues are hampering the growth of the Single-Use Bioreactors Market.
Single-use Bioreactor Market – Landscape:
Product launches, technological advancements, mergers and acquisitions, partnerships, and joint ventures are key strategies adopted by players in the Single-use Bioreactor Market. Key companies of this market include:
Acquisitions/Product Launches:
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Key Takeaways
Related Reports:
A. Membrane Bioreactor System Market
https://www.industryarc.com/Research/Membrane-Bioreactor-System-Market-Research-500374
B. Single-use Bioprocessing Market
https://www.industryarc.com/Report/16720/single-use-bioprocessing-market.html
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