3-Nitro-o-Xylene Market is forecast to reach US$1.8 billion by 2026, after growing at a CAGR of 6.5% during 2021-2026. The rising demand is atrributed to the increased consumption of chemical intermediates in pharmaceutical and agrochemicals is estimated to grow the market size. 3-Nitro-o-Xylene is a liquid nitro compound, also called 1, 2-Dimethyl-3-nitrobenzene; 3-Nitro-1, 2-dimethylbenzene, which have one or more nitrogen oxides groups. It is highly soluble in water and can withstand at high temperatures approximately 245 0C. 3-Nitro-o-Oxylene is a pure (<98% to < 99%) liquid with a yellow appearance and a versatile intermediate that is used in pharmaceutical, organic synthesis, agrochemicals, and other applications. Thus, the growing pharmaceutical industry is expected to drive the demand for 3-Nitro-o-Xylene. According to the National Healthcare of United States, healthcare spending increased 4.6 percent to reach $3.8 trillion in 2019. Additionally, 3-Nitro-o-Xylene is used in the production of anti-inflammatory analgesic mefenamic acid which is used to treat menstrual pain. Hence, due to growing usage of this chemical is estimated to grow the 3-Nitro-o-Xylene market.
Impact of COVID-19
During 2020 and Q2 of 2021, major sectors saw a steady decline in growth owing to the decrease in transportation during the lockdown pandemic. But the medical sector saw growth during the pandemic. The rise in consumer awareness about the uses of pharmaceutical intermediates encourages a positive attitude towards using of 3-Nitro-o-Xylene.
3-Nitro-o-Xylene Market Segment Analysis – By Purity
98% to 99% purity segment held the largest share in the global 3-Nitro-o-Xylene market in 2020. With this purity, 3-Nitro-o-Xylene can supply 200kg/drum for agrochemicals. They can handle vapor pressure at 13 Pa with a density of 1.129 g/cm3 at 25 °C (77 °F). Thus, this purity of 3-Nitro-o-Xylene is used as a chemical intermediate for the manufacturing of dyes and explosives chemicals, which is expected to drive the market growth.
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3-Nitro-o-Xylene Market Segment Analysis – By Packaging
Drum packaging held the largest share in the global 3-Nitro-o-Xylene market in 2020. By using drum packaging, the liquid is safely provided to manufacturers. 3-Nitro-o-Xylene is available in liquid form and contains a maximum of 0.2% moisture, thus with the help of drum packaging its supplement is very convenient and ecofriendly. Hence, drum packaging is widely used for the packing of 3-Nitro-o-Xylene.
3-Nitro-o-Xylene Market Segment Analysis – By Application
Pharmaceutical application segment has dominated the market for the 3-Nitro-o-Xylene market in 2020 and is growing at a CAGR of 6.8% during 2021-2026. 3-Nitro-o-Xylene is a liquid chemical intermediate used as a pharmaceutical intermediate for the production of mefenamic acid which is significant in the treatment of menstrual pain. Mefenamic acid is extensively designed in the pharmaceutical industry to decrease inflammation which is encouraging the public and private pharmaceutical investment and is also expected to grow the market size. According to the National Investment Promotion and Facilitation Agency, India is the largest producer of generic medicines which contributes 20% share globally for the exportation of generic medicines. Hence, such factors are estimated to grow the market size.
3-Nitro-o-Xylene Market Segment Analysis – By Geography
Asia Pacific dominated the 3-Nitro-o-Xylene market share with more than 30% in 2020 followed by North America due to growing pharmaceutical and agriculture production in Indian, China, and other countries. 3-Nitro-o-Xylene act as an intermediate for manufacturing pharmaceutical products and agrochemicals. According to India Brand Equity Foundation (IBEF), India’s domestic pharmaceutical market is estimated at US$ 41 billion in 2021. The sector is also expected to reach US$ 65 billion by 2024 and ~US$ 120-130 billion by 2030. Additionally, North America has also contributed a significant share for the 3-Nitro-o-Xylene market due to growing investment in the pharmaceutical sector. According to the American Society for Aesthetic Plastic Surgery (ASAPS), in the United States, patients spent US$ 761 million on breast lift surgery, US$ 358 million on eyelid surgery, and US$ 1.1 billion on silicone breast implant surgery in 2018. Hence, growing end-use industries in Asian and North American countries are estimated to boost the demand for 3-nitro-o-xylene.
3-Nitro-o-Xylene Market Drivers
Growing Consumption of 3-Nitro-o-Xylene
The 3-Nitro-o-Xylene is used to manufacture agrochemicals and act as an intermediate for manufacturing of dyes and explosive chemicals, which is increasing the consumption of the liquid chemical intermediates. According to the Government of India Ministry of Chemicals & Fertilizers Department of Chemicals and Petrochemicals, the pesticide agrochemical production increased by 217 thousand million tons in 2018-2019 compared to 213 thousand million tons in 2017-2018. Additionally, organic chemicals production also increased during 2018-1019 by 1884 thousand million tons compared to 1799 thousand million tons during 2017-2018. Hence, the increasing production of crops is also growing the demand for agrochemicals which, in turn, is estimated to grow the market size. According to the Organization for Economic Co-operation and Development (OECD) and Food and Agriculture Organization (FAO), world wheat production is forecast to increase by 3.7 tonnes/hectare in 2025 from 3.5 tonnes/hectare in 2020. Additionally, India is the second-largest county after China for wheat production. In India, wheat production increased by 3.509 tonnes/hectare to 3.716 tonnes/hectare during 2021-2025. Hence, such factors are increasing the 3-Nitro-o-Xylene market size during the projected year.
Rising Cases of Hospital Acquired Infections
An endometrium tissue lining is found outside of the uterus which tissue bleed during the menstruation cycle, they can cause swelling, scarring, and pain. According to the Indian Government, 50% of women facing menstrual disorders which cause PCOS, anemia, and others. Additionally, according to the Centers for Disease Control (CDC), hospital-acquired infections an estimated at 1.7 million infections and 99,000 associated deaths every year. Of which, 32 % are urinary tract infections, 22 % are surgical site infections, 15% are lung infections, and other infections. Thus, increasing menstrual and other diseases is estimated to grow the demand for 3-Nitro-o-Xylene
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3-Nitro-o-Xylene Market Challenges
Health Hazardous with 3-Nitro-o-Xylene
3-Nitro-o-Xylene is an odorless liquid chemical intermediate that is insoluble in water and is produced toxic fumes upon decomposition on heating. During decomposition of heating, it releases hazardous products such as carbon oxides and nitrogen oxides. Carbon oxides cause headaches, dizziness, increased heart rate, elevated blood pressure, coma, asphyxia, and other disorders. Thus, the exposure of the nitrogen group may limit the demand for 3-Nitro-o-Xylene.
3-Nitro-o-Xylene Market Landscape
Technology launches, acquisitions, and R&D activities are key strategies adopted by players in the 3-Nitro-o-Xylene Market. Major players in the 3-Nitro-o-Xylene Market include:
VWR International, LLC
Deepak Nitrite Limited
YC BIOTECH (JIANGSU) CO., LTD.
Shaanxi Kangyuan Chemical Co., Ltd.
Alfa Aesar, and among others.
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Asia Pacific dominates the market of the 3-Nitro-o-Xylene market due to the growing pharmaceutical and agriculture industry in developing and emerging countries of Asia Pacific.
According to the India Brand Equity Foundation (IBEF), the healthcare market is expected to increase by Rs. 8.6 trillion (US$ 133.44 billion) by 2022, which, in turn, is expected to drive the demand for 3-nitro-o-xylene market.
Additionally, China is one of the major producers of rice. According to the Organization for Economic Co-operation and Development (OECD) and Food and Agriculture Organization (FAO), rice production in China increased by 5.0 tonnes/hectare in 2021 compared to 4.9 tonnes/hectare in 2019.
3-Nitro-o-Xylene produce mefenamic acid for menstrual pain treatment, which is growing the demand for this pharmaceutical chemical intermediates.
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