Oral administration of vaccines is the most convenient way of vaccination due to several factors such as oral vaccines are invasive, safe and suitable for all groups of age, especially the children. Oral vaccines are predominantly used for mass vaccination and are mostly filled with liquid sachets or blisters. For diseases such as typhoid, cholera, adenovirus, rotavirus, and others, oral vaccines are generally available.
The next level of immunization has been taken by oral vaccination. Most of the vaccines are parenteral, but the oral route is cost-effective and feasible for certain vaccines for combating non-mucosal infections transmitting the gastric environment. Positive patient compliance to oral vaccination has been shown to be positive.
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Major Drivers, Restraints, Challenges and Opportunities
The global market for oral vaccines is driven primarily by the increasing prevalence of infectious diseases, bio-terrorism, existing vaccine resistance, etc. In addition, the growth of the worldwide market for oral vaccines is expected to be fuelled by the fact that patients adhere to needle-free vaccines regime, preference for children’s and geriatric oral vaccines, cost-effectiveness, FDA approval of oral vaccines for conditions such as cholera etc.
The oral vaccines market are significantly driven by removal of needles and their safe, cost-effective characteristics. Some of the other factors expected to drive the market are the rising prevalence of infectious diseases in developing countries, vaccine resistance and bioterrorism. In addition, increased government support is expected to drive growth for new product approvals.
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By application, the public segment is projected to dominate the oral vaccines market during the forecast period. The government’s involvement in preventing and treating infectious diseases and increasing investment by key research and development players in developing effective medicines is helping the segment to grow.
Among all product types, the oral polio vaccine accounted for the largest revenue share and is expected to progress ahead with the same trend during the forecast period, owing to its increasing adoption for safety and efficacy coupled with rise in efforts from several governments to completely eliminate the cases of polio from their countries.
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North America, with its highly scheduled healthcare repayment schemes and the power of costly vaccines purchasing, is expected to lead the global market. In developing countries with a large incidence of infectious diseases, oral vaccines have special advantages, and simple logistical systems for oral vaccines are highly efficient in mass immunization programs.
Asia-Pacific is anticipated to witness considerable growth in the oral vaccines market as government efforts and various vaccine campaigns increase. According to Nano Letters, an American Chemical Society journal, orally vaccines with micromoteurs have been developed by researchers. In order to enhance the usefulness of vaccines, the microengines prevent the active agents in vaccine from acidic condition in the stomach.
The key players in the oral vaccines market are focusing on strategic merges and expansions to promote their product worldwide. Key players present in the market are Abbott Biologicals, Serum Institute of India pvt ltd, Valneva Canada, Sanofi, Paxvax corporation ltd, Novavax, GlaxoSmithKline, Janssen pharmaceuticals, Merck, and Shanghai Bravo bio Co ltd.
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