According to The Insight Partners market research study titled ‘Whole Exome Sequencing Market to 2027 – Global Analysis and Forecasts by Product & Service, Technology, Application and Geography. The global whole exome sequencing market is expected to reach US$ 3,812.0 Mn in 2027 from US$ 755.68 Mn in 2018. The market is estimated to grow with a CAGR of 19.8% from 2019-2027. The report highlights the trends prevalent in the global whole exome sequencing market and the factors driving the market along with those that act as challenges to its growth.
(**Note: The sample of this report is updated with COVID-19 impact analysis**)
To Know How COVID-19 Pandemic Will Impact Global Whole Exome Sequencing Market | Get a Sample Copy of Report, Click Here: https://www.theinsightpartners.com/sample/TIPRE00005519/
Global whole exome sequencing market was segmented by product & service, technology, and application. On the basis of the product & service, the market is segmented as systems, kits and services. Services segment is further sub-segmented into sequencing services and data analysis (bioinformatics) and other services. Based on the technology, the whole exome sequencing market is segmented into sequencing by synthesis, ion semiconductor sequencing and other technologies. On the basis of the application, the whole exome sequencing market is segmented into diagnostics, drug discovery & development, personalized medicine and others. Diagnostics segment is further sub-segmented into cancer diagnostics, monogenic (mendelian) disorders diagnostics, monogenic types of diabetes diagnostics and HIV diagnostics and other diagnostics.
The market for whole exome sequencing is expected to grow significantly due to factors such as reduction in time and cost for sequencing, rising need of molecular diagnosis and increasing application in drug discovery are likely to drive the growth of the whole exome sequencing market.
The major players operating in the whole exome sequencing market include, Thermo Fisher Scientific Inc., Illumina, Inc., Centogene AG, F. Hoffmann-La Roche AG, Psomagen, Inc. (previuosly Macrogen Corp.), Pacific Biosciences of California, Inc., Brooks Automation, Inc. (GENEWIZ, Inc.), Bio-Rad Laboratories, Inc., Eurofins Scientific and Stratos Genomics. The market has carried out various organic and inorganic growth strategies in the market which has assisted in strengthening their product offering in the market.
Global Whole Exome Sequencing Market, By Regions, 2018 (%)
Reduction in Time and Cost for Sequencing
The exon is part of a genome which is responsible for making 1 or 2 percent of the entire genome of a person. All of the exon in a genome are together known as the exome. And thus, sequencing is of these is known as whole-exome sequencing. The whole-exome sequencing allows identifying the variations in the protein-coding sites of any gene compared to sequencing a few genes together. The whole-exome sequencing is preferred widely due to its property to identify a mutation in a single exon. Identifying mutation in at the original site makes whole-exome sequencing an efficient method and enable to identify possible disease-causing mutation.
The advancement in the field of genomics has led to a significant reduction in the time and cost of genome sequencing. The related cost of sequencing with different sequencing techniques and strategies are of interest as they influence the scope and scale of the genomic research studies. Thus, it makes whole-exome sequencing much-preferred method than whole-genome sequencing.
The advantages of exome sequencing have resulted in the reduction of time and cost to a great extent. Approximately 2% of the genome is sequenced by the WES method; however, it generally sequences the exon at a deeper level it sequence to 100X. The technique enables sequencing through a process where the DNA and RNA are hybridized with the protein-coding site and is isolated from the non-coding site. Also, the data required for 100X sequencing is approximately 5- 6GB, whereas, in genome sequencing, it is nearly 90GB. Thus, these factors offer lower data storage, faster, cheaper, and more accessible data analysis. Therefore, owing to the above-mentioned factors, it is estimated that the market for whole-exome sequencing is likely to grow significantly during the forecast period.
Rising Need of Molecular Diagnosis
The whole-exome sequencing has been accepted as an advanced sequencing technique due to its advantages. Due to the benefits of whole-exome sequencing, it is used as a diagnostic tool in regular practice. The technique is mainly used to diagnose genetic diseases and cancer. The use of exome sequencing is offered genetic analysis that allows appropriate treatment, management, inheritance, and efficient decision making.
The whole-exome sequencing technique is used as it provides information on clinically covered all genes. The technique analyzes conditions for single gene and multi gene disorders. The whole-exome sequencing technique is considered ideal for targeted management of complex conditions such as epilepsy, ASDs, neuropathy, and other genetic diseases. In addition, the whole-exome sequencing allows complete analysis of nearly 23,000 genes in the human genome with the help of next-generation sequencing in a single run.
The whole-exome sequencing is a short-term substitute for receiving an image of a genome that is being coded. Whole-exome sequencing is attractive in the fields of research, diagnostics, and clinical setting. The whole-exome sequencing is used for identifying variants in both all the disease types and in SNPs associations and pharmacogenetics.
Thus, the wide application of the whole-exome sequencing in the field of molecular diagnostics and clinical diagnostics are likely to influence the growth of the market during the forecast period.
Product & Services Type Insights
The global whole exome sequencing market by product & services segments was led by kits. In 2018, the kits segment held a largest market share of the whole exome sequencing market, by product & services. Also, the kits segment is expected to be the fastest growing segments of the market in 2027 owing to presence of a large number of manufacturers like Thermo Fisher Scientific, Illumina, etc. and also these kits are frequently used in various research processes that further is expected to propel growth of the whole exome sequencing market.
The report segments the global whole exome sequencing market as follows:
Global Whole Exome Sequencing Market – By Product & Service
Global Whole Exome Sequencing Market – By Technology
Global Whole Exome Sequencing Market – By Application
Purchase a copy of the Global Whole Exome Sequencing Market report https://www.theinsightpartners.com/buy/TIPRE00005519/