Involved pharmaceutical companies in the Thrombotic Thrombocytopenic Purpura market are Takeda, Lee’s Pharmaceutical and others.
DelveInsight’s Thrombotic Thrombocytopenic Purpura Pipeline Report provides a disease overview, pipeline scenario and therapeutic assessment of the key pipeline therapies in this domain. This report gives a detailed clinical and non-clinical stage products analysis. The TTP report also highlights the unmet needs with respect to the development of Thrombotic Thrombocytopenic Purpura.
Some of the key highlights from the Thrombotic Thrombocytopenic Purpura Pipeline Report-
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Thrombotic Thrombocytopenic Purpura (TTP) is a rare, life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anaemia, severe thrombocytopenia, and organ ischemia with profound thrombocytopenia. TTP is characterized by a severe deficiency in ADAMTS13 (a disintegrin & metalloprotease with thrombospondin type 1 repeats, member 13), the specific von Willebrand factor (vWf)-cleaving protease.
BAX 930/ TAK755/SHP655 (Shire) is a fully glycosylated recombinant human ADAMTS-13 protein that restores the missing enzyme in a patient’s blood without the risk for complications for human-donor plasma.
The FDA has been granted fast track designation to BAX930 for the therapy of acute episodes of hereditary TTP in patients with a constitutional deficiency of the von Willebrand factor-cleaving (VWF) protease ADAMTS13.
Currently, the drug is in phase III trial, which aims to assess the safety & efficacy of BAX 930 in the prevention & treatment of acute episodes of thrombotic thrombocytopenic purpura in participants with severe congenital deficiency of ADAMTS13.
Anfibatide (Lee’s Pharmaceutical) is a snake venom-derived protein that acts as a platelet glycoprotein Ib antagonist. It is in Phase II studies being evaluated as adjuvant therapy for plasma exchange in patients with acquired TTP. The drug has received an orphan designation for TTP from the US FDA.
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Key Pipeline Therapies along with Companies
By Product Type
By Route of Administration
By Molecule Type
By Mechanism of Action
By Stage and Route of Administration
By Stage and Product Type
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Scope of the Report
Table of content
|2||Thrombotic Thrombocytopenic Purpura|
|3||Thrombotic Thrombocytopenic Purpura Current Treatment Patterns|
|4||Thrombotic Thrombocytopenic Purpura DelveInsight’s Analytical Perspective|
|6||TTP Late Stage Products (Phase-III)|
|7||TTP mid Stage Products (Phase-II)|
|8||Thrombotic Thrombocytopenic Purpura Early Stage Products (Phase-I)|
|9||Pre-clinical Products and Discovery Stage Products|
|12||TTP Discontinued Products|
|13||TTP Product Profiles|
|14||Thrombotic Thrombocytopenic Purpura Key Companies|
|15||TTP Key Products|
|16||Dormant and Discontinued Products|
|17||Thrombotic Thrombocytopenic Purpura Unmet Needs|
|18||Thrombotic Thrombocytopenic Purpura Future Perspectives|
|19||Thrombotic Thrombocytopenic Purpura Analyst Review|
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