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DelveInsight’s Oncolytic Virus Cancer Therapy Pipeline Insights report provides a comprehensive outlook of the pipeline therapies in different clinical and preclinical stages of development, their launch, and how the market is expected to transform in the aftermath across the Oncolytic Virus Cancer Therapy domain.
The ‘Oncolytic Virus Cancer Therapy Pipeline Analysis – 2021’ report provides a 360-degree view of the therapeutics environment for Oncolytic Virus Cancer Therapy emerging therapies by development point, product type, route of administration, molecule type, and MOA.
The Oncolytic Virus Cancer Therapy pipeline report lays down the business opportunities, threats, future collaborations, strong competitors, and growth strategies.
Some of the key highlights from the Oncolytic Virus Cancer Therapy Pipeline Report:
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Oncolytic virus (OV) cancer therapies are the virus-based therapeutic strategies that infect and destroy cancer cells and act as an in situ cancer vaccine by releasing tumour-specific antigens. Viruses such as myxoma virus or reovirus have inherent selectivity to tumour cells while being nonpathogenic to healthy human cells. On the other hand, other OVs, including adenovirus, herpes simplex virus type-1 (HSV-1), and vesicular stomatitis virus (VSV), have been genetically engineered to function as vectors to boost anti-tumour immune responses. The anti-tumour efficacies of these OVs have been evaluated in many preclinical and clinical studies as monotherapy and combination therapy.
Oncolytic Virus Cancer Therapy Pipeline Analysis: Drug Profile
CG0070: CG Oncology
CG0070 is investigational oncolytic immunotherapy based on a modified common cold adenovirus backbone that contains a cancer-specific promoter and a GM-CSF transgene. CG0070 first replicates inside the tumour’s cells, causing tumour cell lysis and immunogenic cell death. Then, the rupture of the cancer cells can release tumour-derived antigens, along with GM-CSF, that can stimulate a systemic antitumor immune response that involves the body’s white blood cells. CG0070 is in development for various solid tumour types to be used alone or with immune checkpoint modulators.
ONCOS-102: Targovax
ONCOS-102 is a genetically modified oncolytic adenovirus, which has been engineered to selectively infect cancer cells and activate the immune system to fight cancer. ONCOS-102 is currently being tested in mesothelioma, melanoma and peritoneal malignancies and has shown promising clinical results both as monotherapy and in combination with chemotherapy and a checkpoint inhibitor. In February 2021, Targovax announced that ONCOS-102 had received Fast-Track designation in malignant pleural mesothelioma from the US FDA.
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Key Pipeline Therapies along with Companies
Oncolytic Virus Cancer Therapy Pipeline Therapeutics Assessment
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Scope of the Report
Table of Contents:
| 1. | Report Introduction |
| 2. | Oncolytic Virus Cancer Therapy |
| 3. | Oncolytic Virus Cancer Therapy Current Treatment Patterns |
| 4. | Oncolytic Virus Cancer Therapy – DelveInsight’s Analytical Perspective |
| 5. | Therapeutic Assessment |
| 6. | Oncolytic Virus Cancer Therapy Late Stage Products (Phase-III) |
| 7. | Oncolytic Virus Cancer Therapy Mid Stage Products (Phase-II) |
| 8. | Early Stage Oncolytic Virus Cancer Therapy Products (Phase-I) |
| 9. | Oncolytic Virus Cancer Therapy Preclinical Products and Discovery Stage Products |
| 10. | Inactive Products |
| 11. | Dormant Products |
| 12. | Oncolytic Virus Cancer Therapy Discontinued Products |
| 13. | Oncolytic Virus Cancer Therapy Product Profiles |
| 14. | Oncolytic Virus Cancer Therapy Key Companies |
| 15. | Oncolytic Virus Cancer Therapy Key Products |
| 16. | Dormant and Discontinued Products |
| 17. | Oncolytic Virus Cancer Therapy Unmet Needs |
| 18. | Oncolytic Virus Cancer Therapy Future Perspectives |
| 19. | Oncolytic Virus Cancer Therapy Analyst Review |
| 20. | Appendix |
| 21. | Report Methodology |
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