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With over 85 microbiome-based, live biotherapeutic products under preclinical and clinical development, the demand for R&D and manufacturing services for such products is anticipated to increase beyond the capabilities of innovator companies alone
Roots Analysis has announced the addition of “Live Biotherapeutic Products and Microbiome Contract Manufacturing Market, 2020-2030: Focus on Active Pharmaceutical Ingredients and Finished Dosage Forms, 2020-2030” report to its list of offerings.
Manufacturing live biotherapeutic products is both technically challenging and financially demanding; as a result, innovator firms are becoming increasingly reliant on contract service providers to access specialized facilities and optimize overall costs.
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Key Market Insights
Over 25 players claim to provide microbiome-based live biotherapeutics contract manufacturing
More than 80% of the companies engaged in this domain are mid-sized and large firms; examples of firms established in 2019 include Arranta Bio and BacThera (a Lonza and Chr. Hansen joint venture). Further, nearly 50% of the CMOs have established the necessary expertise for handling both anaerobic and aerobic strains.
35+ manufacturing facilities focused on live biotherapeutics have been established worldwide
Majority (~55%) of the manufacturing facilities are located in Europe, followed by North America. Prominent manufacturing hubs in the Europe include (in decreasing order of number of manufacturing facilities) the UK, France, the Netherlands, Italy, Germany, Switzerland, and Sweden.
Approximately 88% of the total installed capacity is dedicated to commercial scale manufacturing
Whereas, rest (~10%) of the capacity is being used for preclinical / clinical scale manufacturing of microbiome products. In addition, over 60% of the total current global, installed manufacturing capacity is installed in Europe.
Over 170 registered clinical trials involved the use of microbiome-based live biotherapeutics
Majority of these studies are being conducted at various hospitals / centers across the US. Examples of leading non-industry players include (in decreasing order of number of trials) University of California, National Institute of Allergy and Infectious Diseases, Radboud University, and The University of Texas Health Science Center.
The global clinical demand for microbiome-based live biotherapeutic products is anticipated to grow at a CAGR of 23%, between 2020 and 2030
By 2030, over 31,000 patients are estimated to be enrolled in the clinical trials involving the use of microbiome-based live biotherapeutics. Industry players are anticipated to contribute majority (over 60%) of the demand in the short-term as well as long-term.
Several big pharma players are actively engaged in the microbiome live biotherapeutics domain
In fact, leading pharmaceutical companies have partnered with smaller business entities to develop manufacturing capabilities related to microbiome-based therapies / diagnostics. Examples of such small ventures with players with in-house capability include (in alphabetical order) Assembly Biosciences, Enterome Bioscience, Finch Therapeutics and NuBiyota.
By 2030, North America and Europe are anticipated to capture over 85% of the market opportunity
In terms of type of product manufactured, APIs currently represent the highest share (58%); this trend is unlikely to change in the foreseen future.
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Key Questions Answered
The USD 300 million (by 2030) financial opportunity within the microbiome contract manufacturing market has been analysed across the following segments:
Type of Product Manufactured
Type of Type of Formulation
Scale of Operation
Key Geographical Regions
The report features inputs from eminent industry stakeholders, according to whom the microbiome therapeutics contract manufacturing services market is likely to witness substantial growth in the foreseen future. The report includes detailed transcripts of discussions held with the following experts:
The research covers detailed profiles brief profiles of several companies (including those listed below); each profile features an overview of the company, its financial information (if available), microbiome-related service portfolio, facilities dedicated to microbiome manufacturing, and an informed future outlook.
For additional details, please visit
https://www.rootsanalysis.com/reports/view_document/human-microbiome-market/281.html or email email@example.com
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