Zion Market Research has published a new report titled “Natural Killer Cells Therapeutics Market by Therapeutics (Antibodies Directed by NK Cell and NK Cell Therapies); by Application (Immunoproliferative Disorders, Gastrointestinal Diseases, Cancer and Other Applications); by End User (Hospitals, Research Centers & Institutes and Other End Users): Global Industry Perspective, Comprehensive Analysis and Forecast, 2018 – 2025”. According to the report, global demand for natural killer cells therapeutics market was valued at approximately USD 1.41 billion in 2018, and is expected to generate revenue of around USD 4.19 billion by end of 2025, growing at a CAGR of around 16.9% between 2019 and 2025.
Natural killer cells also known as NK cells or K cells are type of lymphocytes (white blood cells) which are integral part of innate immune system. Natural killer cells are also killer cells that play crucial role in host rejection of tumor cells and virally infected cells. Natural killer cells comprise of special proteins in their cytoplasm that are cytotoxic in nature like proteases, perforins. These proteins assist in the process of apoptosis. Perforin aids in formation of pore in cell membrane of target cells to allow proteases to enter into the cells through these pores to induce apoptosis. Interferons or macrophage-derived cytokines activate the NK cells. Patients with deficiency of NK cells are highly susceptible to herpes virus infection. NK cells are being widely used as therapeutics against malignancies and viral infections as they generate immune response.
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The global market for natural killer cells therapeutics is fueled mainly due to growing use of NK cells for treatment of liver diseases, cancer, viral infections, etc. NK cells have importance in immune surveillance of tumor cells and thus have gained cognizance in cancer therapeutic applications. Additionally, market growth is supported by growing R&D investments to expand use of NK cells in wider range of applications and increasing cancer immunotherapy awareness across the globe. However, high cost of treatment, lack of specificity and low survival rate of natural killer cells in-vivo may hinder the market growth over the forecast period. Emerging markets with increasing cancer prevalence and high unmet medical needs are projected to open new growth avenues for key market players in the global natural killer cells therapeutics.
The market is segmented based on end user, application, therapeutics and region. NK cell directed antibodies and NK cell therapies are therapeutics segments of, NK cells therapeutics market. In 2018, NK cell directed antibodies held largest revenue share and are anticipated to exhibit highest growth during the forecast period. This high growth is attributed to increasing use of natural killer cells therapeutics due to growing awareness about immunotherapies and growing R&D investments to develop novel therapeutics for cancer treatment.
Based on application global market is split into cancer, gastrointestinal diseases, immunoproliferative disorders, and other applications. Cancer was dominating application segment in 2018 and will retain its dominance in the coming years. Growing prevalence of cancer across the globe, increasing research and investments for innovative cancer therapy development are important factors that support the growth of cancer application segment.
Research centers & institutes, Hospitals, and others are end users of the natural killer cells therapeutics market. Hospitals were the largest end user segment of the market due to growing usage of NK cell therapies for cancer and various other therapeutic applications worldwide. Highest growth is projected for research centers & institutes in the coming years owing to increasing number of research projects and increasing R&D investments.
At regional level, North America was the largest market in 2018 for global natural killer cells therapeutics. This large share is attributed to growing cancer prevalence, wide adoption of immunotherapies due to awareness and lesser side effects, surge in research projects and R&D investments in this region. Europe was second leading regional market. Germany, U.K. and France were leading country level markets in Europe natural killer cells therapeutics market. Market growth in Europe is fueled by various factors such as availability of developed infrastructure, increasing cancer prevalence, increasing demand for cancer therapies with minimal side effects and increasing awareness. Latin America is anticipated to observe modest growth over the forecast timeframe. Asia Pacific region is forecasted to exhibit fastest growth for natural killer cells therapeutics market over the forecast period. Major factors that are expected to boost market growth in Asia Pacific are growing prevalence of cancer, increasing geriatric population base, increasing R&D investments and increasing awareness. Middle East and Africa is projected to witness considerable growth in the coming years.
Major players included in the report are Nkarta Therapeutics, Inc., NKT Therapeutics Inc., Innate Pharma S.A., Nantkwest Inc., Fortress Biotech, Glycostem Therapeutics BV, Celgene Corporation, Fate Therapeutics, Ziopharm Oncology Inc. and Affimed N.V. among others.
The report segment of global natural killer cells therapeutics market as follows:
Global Natural Killer Cells Therapeutics Market: By Therapeutics
Global Natural Killer Cells Therapeutics Market: By Application
Global Natural Killer Cells Therapeutics Market: By End User
Global Natural Killer Cells Therapeutics Market: By Region
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