Amniotic Membrane Market size is forecast to reach $4.37 billion by 2025, growing at a CAGR of 11.56% during the forecast period 2020-2025. Amniotic membrane, also called amnion, is the innermost layer of the placenta and consists of a thick basement membrane and an avascular stromal matrix. The amniotic membrane is the innermost, avascular layer of fetal membranes-composed of the epithelium, basement membrane and stroma-collected from full-term placental tissue and treated with antibiotics during collection. Those layers contain properties that each play an important role in healing. Amniotic membrane transplantation has been used as a graft or as a dressing in different surgical subspecialties. Rise in demand of transplants with tissue based products, increasing investments in R&D activities of stem cells, growing frequencies of eye disorders in the geriatric population and increase in awareness about advantages of amniotic membrane transplants are major factors that are driving the market growth in recent years. In addition, major product launches by key market players like Amnio Technology, Llc and Integra LifeSciences are other factors driving the growth of the market.
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Product – Segment Analysis
Cryopreserved Amniotic Membrane held the largest share in the product segment of Amniotic Membrane Market in 2019 and is estimated to grow at a CAGR of 9.21% during the forecast period 2020-2025. FDA had approved the cryopreserved tissue to deliver anti-inflammatory, anti-scarring and anti-angiogenic actions and to promote epithelial healing. Also, applying amniotic membrane speeds up the cell regeneration process, which provides a greater advantage for quicker treatment and recovery for Prokera treatment of dry eye disease (DED). The cryopreserved amniotic tissue is processed using the proprietary CryoTek technology (Bio-Tissue), which has been proven to preserve the biological properties of amniotic membrane and umbilical cord tissue. These biological components that have been shown to play a major role in controlling inflammation and preventing scarring, include the Heavy Chain Hyaluronic Acid/Pentraxin-3 complex (HC-HA/PTX3). Other factors that contribute to the growth of this segment are the increasing product launches by key market players and application in other medical conditions owing to its healing and efficacy effects. Lyophilization Amniotic Membrane segment is set to be the fastest growing segment and is estimated to register the highest CAGR during the forecast period 2020-2025, owing to their easier and longer storage, and increasing investments in its applications in ophthalmology.
Application – Segment Analysis
Surgical Wound held the major share in the application segment of Amniotic Membrane Market in 2019. Amniotic Membrane is used in surgical wounds, as it contains a significant number of cytokines and essential growth factors, reduces pain when applied to a wound, increases, and enhances the wound healing process, has antibacterial properties and is non-immunogenic. Increasing number of surgical procedures in hospitals and ambulatory surgical centers (ASCs), preference of painless wound healing and versatility of amniotic membrane on any type of wounds drives the market growth of this segment. Ophthalmology segment is forecast to continue growing at the fastest rate with the highest CAGR during the forecast period 2020-2025, owing to the ever-increasing rate of eye problems among people of all ages, numerous applications like reconstruction and grafting for ocular surface melts, and key investments by key market players.
Geography – Segment Analysis
North America dominated the geography segment of Amniotic Membrane Market with a share of more than 41.6% in 2019, followed by Europe. Growing incidences of eye disorders among the old aged people, increasing healthcare affordability of the average citizen and presence of key market players in the region have helped in the growth of Amniotic Membrane Market infrastructure in this region. Cataract (42.2%), age-related macular degeneration (28.1%), others (22.7%), diabetic retinopathy (4.7%) and glaucoma (2.3%) are major eye diseases occurring in the U.S., which are forecast to increase. Increased health policy planning and investments by the big market players are set to fuel the market growth in the next few years. Europe held the second place in the geography segment share of the market, owing to increasing health awareness among the masses, growing prevalence of cicatricial pemphigoid and conjunctival surface reconstruction, and increasing government expenses for providing better healthcare to the masses.
Asia-Pacific is estimated to grow at the fastest rate at a higher CAGR during the forecast period 2020-2025. This is owing to rising incidence of burn injuries and chronic diseases, and increasing eye diseases among the geriatric population.
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Drivers – Amniotic Membrane Market
Higher success rate (65% to 80%), low rate of recurrence (20% to 35%) and newly developed methods of tissue preservation have resulted in a surge in number of amniotic membrane transplants in recent years. It is anticipated that the numbers is set to see further increase in the upcoming years, following increased government initiatives and more technological innovations.
Chronic diseases are among the most prevalent and costly health conditions in the U.S. Nearly half (approximately 45%, or 133 million) of all Americans suffer from at least one chronic disease, and the number is growing. Medical burn cases and injuries are also in growing numbers, thereby resulting in greater demand for amniotic membrane. Thus, the market is poised to see significant growth during the forecast period 2020-2025.
Challenges – Amniotic Membrane Market
Recent years saw a shortage in adequate healthcare workers, as well as skilled and professional ones for amniotic membrane market. A shortage of skilled health workers leads to longer wait times for patients in almost every part of the healthcare process. During stays in the hospital, patients are likely to experience longer wait times if they don’t have the staff needed to accommodate them. Thus, it is anticipated to hamper the market growth during the forecast period 2020-2025.
Amniotic Membrane Industry Outlook
Product launches, mergers and acquisitions, joint ventures and R&D activities are key strategies adopted by players in the Amniotic Membrane Market. In 2019, Amniotic Membrane Market share is consolidated by the top players present in the market. Amniotic Membrane Market top 10 companies are Celularity Inc, Amnio Technology, Llc, Applied Biologics Llc, Fziomed Inc, Human Regenerative Technologies, Llc, Integra Lifesciences Holding Corporation, Katena Products, Inc, Mimedx Group Inc and Skye Biologics Inc among others.
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