Cognitive Clarity Inc. is currently raising funds in a Preferred Series A-1 financing. To participate in this round of financing accredited investors please submit a request to obtain further information.
Cognitive Clarity Inc. is a nutraceutical product company that has developed breakthrough nutraceuticals for the aging brain, cognition and memory.
Using this extract, known as PTI-00703®, Cognitive Clarity Inc. has created the world’s first nutraceutical products that target brain “plaques and/or tangles” in aging humans and pets, leading to marked improvement in memory and cognition.
No pharmaceutical drug to date has been approved that demonstrates reduction of both “plaques and tangles”. Cognitive Clarity Inc.’s products stand alone.
At last, we have real solutions to counteract the aging that all humans want to avoid.
As it ages, the human brain loses about 85,000 cortical neurons per day, or about one every second.
Starting in your 20’s, there is a slow but deliberate accumulation of two neurotoxic proteins. The first is known as the “beta-amyloid protein” or Aβ. Beta-amyloid protein deposits in the form of “plaques” (that look like meatballs in the brain under a microscope). These “plaques” have been shown to be instrumental in killing neurons, which leads to a decline in memory and cognition.
The second neurotoxic protein that accumulates in the aging brain is known as the “tau protein” and it forms twisted filaments in neurons, called paired helical filaments or “tangles.” Tangles look like dried spaghetti strands under a microscope, and they also cause neurons in the brain to die.
In Alzheimer’s disease, there are thousands, and hundreds of thousands more plaques and tangles in the brain, leading to severe neurodegeneration (i.e. killing and death of neurons), memory loss and cognitive decline. Similarly, when you have a concussion or blow to the head, like in sports, the brain immediately form tangles that lead to loss of memory, depression, altered mood and states, and the like.
The good news: compounds or agents able to disaggregate and reduce the accumulation of “plaques and/or tangles” have been shown to lead to memory improvement and a reduction in memory decline. The only difference between a healthy brain and an aging brain that could lead to age-associated memory impairment (AAMI), then to mild-cognitive impairment (MCI), and potentially to Alzheimer’s disease, is the number of “plaques and tangles” in the brain. An Alzheimer’s brain contains thousand to tens of thousands of “plaques and tangles” per square mm of brain tissue (usually in the hippocampus and cortex; two memory centers of the brain).
Eliminate or reduce “plaques and tangles”, and you prevent, or even reverse, the harm done that contributes directly to memory and cognitive decline.
There are many brain health supplements on the market today, but none of them have been designed specifically to attack the accumulation of brain “plaques and tangles”.
The inception of The Cognitive Clarity Memory Pill™ was based on early discoveries made by Dr. Snow’s research teams that centered upon the isolation and identification of key brain “plaque and tangle”-reducing and memory-enhancing compounds in a proprietary plant extract from the Amazon rain forest, known as PTI-00703®.
PTI-00703® comes from the Amazon woody vine known as Uncaria tomentosa, or cat’s claw. When placed in combination with a specific oolong tea extract, PTI-00703® markedly “dissolves” and “reduces” both brain “plaques and tangles”, and reduces brain inflammation. Thus “PTI” stands for reducing “Plaques, Tangles, and Inflammation.” In animal model studies, these ingredients resulted in reductions of brain “plaque” load by over 50%, with concurrent improvements in short-term memory by over 50%.
The Cognitive Clarity Memory Pill™, which contains PTI-00703® and this specific oolong tea extract, can dissolve tangles within 15 minutes of interaction. This one-two punch product is being developed as both a dietary supplement (The Cognitive Clarity Memory Pill™ for once-a-day oral dosing) and as a memory beverage (The Cognitive Clarity Memory Beverage™).
Here is a brief look at just the first Cognitive Clarity Inc. products coming to market soon.
This Memory Beverage will be formulated to taste good while having all of the “plaque and tangle” dissolving abilities found in The Cognitive Clarity Memory Pill™ product.
This oral nutraceutical pill will prevent and reduce “tangle” accumulation associated with concussions, Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE), and head trauma, such as is seen in NFL players, other athletes and military personnel.
These products will be the world’s firsts that inhibit and reduce brain “plaques” that occur in aging dogs and cats (known in the scientific literature as Cognitive Dysfunction Syndrome or CDS), and improve their cognition and memory. Aged dogs and cats accumulate “plaques in the brain (and, to a lesser extent, tangles) similar to aged people, and they also exhibit enhanced cognitive and memory impairment.
Cognitive Clarity Inc. products are backed by rigorous scientific research, not just marketing slogans and appealing representatives.
Over 100 issued patents in the Company (20 issued patents cover the composition and use of PTI-00703®)
29,000 hours of documented research (to assess the validity of PTI-00703® and its ingredients for inhibition/reduction of brain “plaques and tangles”)
More than 15 peer-reviewed publications and scientific presentations at U.S. and international meetings
Dr. Alan Snow and Dr. Rudolph Tanzi have been at the forefront of brain aging, Alzheimer’s, memory disorders and the like for the last 25 years. Innovators and entrepreneurs, these two men are arguably the world’s most qualified neuroscientists to lead the development of breakthrough nutraceuticals for the aging brain.
Since the remarkable discovery in the Amazon, we’ve made some incredible headway in our mission to build Cognitive Clarity Inc. into a word-class name pioneering breakthrough nutraceuticals for the aging brain. Here’s a quick play-by-play of where we’ve been, where we’re going, and some of our biggest achievements and milestones to date.
700 kg of nutraceutical ingredients have been acquired and have been moved to an FDA Food Facility at Western Distribution Services LLC in Kent, Washington.
The product is complete, and after a human clinical trial, it will be manufactured and ready for sale via internet subscription sales and in select retail stores. We already have a manufacturing partnership with Paragon Labs in Torrance, CA, to produce The Cognitive Clarity Memory Pill™. We are in discussions with LiDestri Food and Drink to manufacture and bottle The Cognitive Clarity Memory Beverage™.
A 3-month intensive study will determine whether placebo vs study product can significantly improve memory, focus, concentration and executive function. We expect to see improvements in memory and other parameters, within the first few doses of taking the study product.
We are currently in discussions with big retail stores including Walmart, Costco, Right Aid, CVS Pharmacy, Target, GNC and other supplement stores; we are also speaking with several pet food formulation companies, including CK Nutrition (Exeter, New Hampshire), and several consultants that are experts in the pet food industry.
Want to learn more about Cognitive Clarity Inc. and the company’s goals for the future? Make sure to request access to the Business Plan tab of the profile to see how you can get involved!
Dr. Alan Snow – President & CEO
This is the 2nd company Dr. Snow has founded. In his first private company, he successfully raised over $45M in private investor funding, acquired over $16.75M from 14 National Institute of Health Small Business Innovative Research (SBIR) awards, and obtained a prestigious $3.5M LEAPS award from the Michael J. Fox Foundation for Parkinson’s Disease Research, for a total of $62.5M in funding.
Dr. Alan Snow is a world-renowned and recognized authority on aging of the brain, Alzheimer’s disease, Parkinson’s disease, and misfolded protein disorders, leading world-class scientific research teams for over 25 years. He served as a Research Associate Professor of Pathology at the University of Washington for 14 years, and headed one of the leading scientific programs as part of the University of Washington Alzheimer’s Disease Research Center. In 1999, Dr. Snow left the University of Washington to head-up a private Company focused on the development of small molecule drugs to target Alzheimer’s, Parkinson’s and misfolded protein disorders. He leased and then developed new state-of-the-art research laboratories; hired corporate and patent lawyers; regulatory and scientific advisors; recruited a world-class team of research scientists from across the country; and recruited and hired key management positions and consultants. After his company shareholders decided it was time to sell, Dr. Snow arranged to acquire all of the nutraceutical patents from his former company, and helped negotiate a world-wide license agreement with University of Washington to nutraceutical technologies that have been developed for the last 15 years. Dr. Snow is an inventor on over 340 issued patents pertaining to drugs and nutraceuticals (compositions of matter and methods of use), and proprietary screening technologies.
Dr. Rudolph Tanzi – Co-founder and Chief Scientific Advisor
Dr. Rudolph Tanzi is a Professor of Neurology and holder of the Joseph P. and Rose F. Kennedy Endowed Chair in Neurology at Harvard University. At Massachusetts General Hospital, Dr. Tanzi serves as the Vice Chair of Neurology and Director of the Genetics and Aging Research Unit. Dr. Tanzi co-discovered all 3 familial Alzheimer’s disease genes and has won numerous awards, including the two highest awards for Alzheimer’s disease research, The Metropolitan Life Award and the Potemkin Prize. In 2015, he was named by TIME magazine as one of the TIME 100 Most Influential People in the World. Dr. Tanzi also co-authored the NY Times Best Sellers “Super Brain” and “Super Genes” with Deepak Chopra.
Mr. Ryan Morrison – Attorney
Mr. Ryan Morrison of the Law Offices of Ryan Morrison is an expert in contract law and intellectual property, and was the principal who helped negotiate and finalize the exclusive world-wide license with University of Washington to nutraceutical patents and technologies. He assists Cognitive Clarity Inc. with corporate licensing and deal contracting.
Mr. Mark Beatty – Attorney
Mr. Mark Beatty of the Mark Beatty Law Firm represents Cognitive Clarity Inc. in corporate matters and equity financings. Mr. Beatty previously worked for Bill Gates, and the Bill & Melinda Gates Foundation.
Mr. Paul Hunter – Attorney
Mr. Paul Hunter of Foley & Lardner LLP (San Diego) represents Cognitive Clarity Inc. in intellectual property matters.