Jordan and Leah are an expectant married couple dealing with a new level of uncertainty in their relationship. While winding down from an intimate evening together, Jordan receives an alarming phone call concerning his grandmother’s house. He immediately drives out to investigate.
After arriving, while walking up to the house, he is jumped, beaten and mugged. Awaking in a daze, Jordan walks the streets looking for help. He approaches a seemingly innocent man, but quickly finds out that he has stumbled upon a crime in progress. He is swiftly abducted by this man and his family, who is lead by the zealously religious, Edith, whom everyone calls “Mama”.
He finds himself a prisoner in their home. Throughout the night, he is approached by each family member as they respond to his presence. He tries to connect and appeal to each one, as a means to escape with his life.
Bradly, who is an empathetic, kind hearted man, wants to help Jordan but is trapped by the strong armed, persuasion of his more violent, impulsive brother, Seth. Edith “Mama” reveals herself as the epicenter of the power in the home. At first, she is assumed to be compassionate and willing to help Jordan, but he eventually sees that her cunning use of her religious beliefs and opinions have made her more of an obstacle than a way out.